Amoxil - Indications & Dosage

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H. pylori eradication to reduce the risk of duodenal ulcer recurrence: Triple therapy: AMOXIL/ clarithromycin/ lansoprazole

The recommended adult oral dose is 1 gram AMOXIL, 500 mg clarithromycin, and 30 mg lansoprazole, all given twice daily (q12h) for 14 days. (See INDICATIONS AND USAGE.)

Dual therapy:

AMOXIL/ lansoprazole The recommended adult oral dose is 1 gram AMOXIL and 30 mg lansoprazole, each given 3 times daily (q8h) for 14 days. (See INDICATIONS AND USAGE.)

Please refer to clarithromycin and lansoprazole full prescribing information for CONTRAINDICATIONS and WARNINGS, and for information regarding dosing in elderly and renally impaired patients.

Dosing recommendations for adults with impaired renal function:

Patients with impaired renal function do not generally require a reduction in dose unless the impairment is severe. Severely impaired patients with a glomerular filtration rate of <30 mL/ minute should not receive the 875-mg tablet. Patients with a glomerular filtration rate of 10 to 30 mL/ minute should receive 500 mg or 250 mg every 12 hours, depending on the severity of the infection. Patients with a less than 10 mL/ minute glomerular filtration rate should receive 500 mg or 250 mg every 24 hours, depending on severity of the infection.

Hemodialysis patients should receive 500 mg or 250 mg every 24 hours, depending on severity of the infection. They should receive an additional dose both during and at the end of dialysis.

There are currently no dosing recommendations for pediatric patients with impaired renal function.

Directions for Mixing Oral Suspension:

Prepare suspension at time of dispensing as follows: Tap bottle until all powder flows freely. Add approximately 1/ 3 of the total amount of water for reconstitution (see table below) and shake vigorously to wet powder. Add remainder of the water and again shake vigorously. 125 mg/ 5 mL Amount of Water Required for Reconstitution

Bottle Size

150 mL 116 mL

Each teaspoonful (5 mL) will contain 125 mg amoxicillin.