Prinivil - Overdosage & Contraindications

lisinopril

CONTRAINDICATIONS

PRINIVIL ® (lisinopril tablets, Merck Frosst Std.) is contraindicated in patients who:

° are hypersensitve to any component of this product;

° have a history of angioneurotic edema relating to previous treatment with an angiotensin-converting enzyme inhibitor;

° have hereditary or idiopathic angioedema.

OVERDOSAGE

The most likely manifestation of overdosage would be hypotension, for which the usual treatment would be intravenous infusion of normal saline solution. If available, angiotensin II may be beneficial.

Lisinopril may be removed from the general circulation by hemodialysis. (see PRECAUTIONS, Anaphylactoid Reactions during Membrane Exposure)



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