Histoplasmosis - disseminated

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Disseminated histoplasmosis

Fungus

Systemic histoplasmosis

Antifungal medications are prescribed to control the infection. Amphotericin B is the drug of choice. In non-AIDS patients with milder disease, ketoconazole, itraconazole, voriconazole, or fluconazole used for at least 12 months may be effective. AIDS patients should receive long-term oral antifungal therapy (itraconazole is preferred) following initial treatment with amphotericin B.

The disease may progress rapidly and death can occur.

Multiple organs are affected.

Call your health care provider if you develop symptoms of disseminated histoplasmosis, particularly if you have been recently treated for acute or chronic histoplasmosis.

Emergency symptoms include mental status changes and rapid worsening of the condition of the affected person.

Review Date: 11/11/2005
Reviewed By: Cyrus Badshah, M.D., Ph.D., Assistant Professor of Clinical Medicine, College of Physicians and Surgeons, Columbia University; Assistant Attending Physician, Department of Medicine, Division of Infectious Diseases & Medical Director, Chest (TB) Clinic and Directly Observed Therapy Program, Harlem Hospital Center. Review provided by VeriMed Healthcare Network.