Wegener’s granulomatosis

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Adenocarcinoma - chest X-ray

Respiratory system

Wegener's granulomatosis on the leg

Midline granulomatosis

Treatment with corticosteroids, cyclophosphamide, methotrexate, or azathioprine produces long-term remission in over 90% of patients.

Support groups with others who suffer from similar diseases may help patients and their families learn about their diseases and adjust to the changes associated with the treatment.

With treatment, most people recover within months. However, some may develop chronic renal failure.

Without treatment, patients can die within a few months.  

• Chronic kidney failure
• Hemoptysis (coughing up blood)
• Respiratory failure
• Inflammation of the eyes
• Nasal septum perforation (hole inside the nose)
• Rash

Medications used to treat the disease can cause side effects, which may also lead to complications.

Call your health care provider if chest pain, coughing up blood, blood in the urine, or other symptoms of this disorder are present.

Review Date: 08/10/2005
Reviewed By: David A. Kaufman, M.D., Assistant Professor, Division of Pulmonary, Critical Care & Sleep Medicine, Mount Sinai School of Medicine, New York, NY. Review provided by VeriMed Healthcare Network.