Drug-induced cholestasis

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Bile pathway

Cholestasis - drug-induced

If medication is causing the cholestasis, the doctor will probably tell you to stop taking the drug and prescribe an alternative, if possible. DO NOT stop taking medications on your own without talking to your doctor. There is no medicine to reverse drug-induced cholestasis.

Most patients recover, but severe cases may lead to liver failure. Drug-induced cholestasis usually reverses after discontinuation of the medication or drug, although it may take many months for cholestasis to resolve.

• Severe itching
• Diarrhea
• Poor absorption of fat and fat-soluble vitamins

Call your health care provider if you have persistent itching or notice that your skin or eyes are yellow.

Review Date: 07/25/2006
Reviewed By: Jenifer K. Lehrer, MD, Department of Gastroenterology, Frankford-TorresdaleHospital, Jefferson Health System, Philadelphia, PA. Review provided by VeriMed Healthcare Network.