Primary biliary cirrhosis

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Bile pathway

Digestive system

PBC

• Itching
• Jaundice
• Enlarged liver
• Abdominal pain
• Fatty deposits under the skin
• Soft yellow spots on the eyelid
• Fatty stools

Tests that suggest or confirm the disease:

• Liver biopsy
• Mitochondrial antibodies (positive in about 95% of cases)
• Elevated immunoglobulin M level in the blood

Tests that reveal liver dysfunction:

• Liver function tests
• Serum cholesterol and lipoproteins may be increased

Review Date: 05/04/2006
Reviewed By: Jenifer K. Lehrer, MD, Department of Gastroenterology, Frankford-Torresdale Hospital, Jefferson Health System, Philadelphia, PA. Review provided by VeriMed Healthcare Network.