Drug-induced hypothyroidism

• A
• B
• C
• D
• E
• F
• G
• H
• I
• J
• K
• L
• M
• N
• O
• P
• Q
• R
• S
• T
• U
• V
• W
• X
• Y
• Z

Endocrine glands

Thyroid gland

The drug causing the hypothyroidism must be discontinued if possible. However, do not stop taking prescribed medications without first consulting your healthcare provider, as some may cause unpleasant or even life-threatening reactions if not sopped gradually and slowly, or replaced appropriately.

Levothyroxine, a thyroid replacement hormone, is the most commonly used medication to treat this condition. The dose is adjusted to bring TSH to normal levels. After replacement therapy has begun, report symptoms of increased thyroid activity (hyperthyroidism) -- restlessness, rapid weight loss or sweating -- if they occur.

A high-fiber, low-calorie diet and moderate activity can help relieve constipation and promote weight loss, if a period of lowered thyroid activity has led to weight gain.

With early treatment, return to the normal state is usual. However, hypothyroidism will return if the replacement therapy is not continued. Myxedema coma can result in death.

Myxedema coma, the most severe form of hypothyroidism, is rare. It can be caused by an infection, illness, exposure to cold, or certain medications. Symptoms and signs of myxedema coma include unresponsiveness to stimulation (decreased consciousness), decreased breathing, low blood pressure, low blood sugar, and below-normal body temperature.

Other complications of hypothyroidism are heart disease, infertility, miscarriage in pregnant women, and pituitary tumors (extremely rare).

Call your health care provider if you have signs or symptoms of hypothyroidism.

Review Date: 08/08/2006
Reviewed By: Robert Hurd, MD, Department of Biology, College of Arts and Sciences, Xavier University, Cincinnati, OH. Review provided by VeriMed Healthcare Network