Zollinger-Ellison syndrome

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Endocrine glands

Z-E syndrome; Gastrinoma

• Pain
• Vomiting blood (occasional)
• Diarrhea

• The gastrin level is increased.
• A secretin stimulation test is positive.
• A calcium infusion test is positive.
• An abdominal CT scan shows a tumor (or tumors) in the pancreas or early small bowel.
• An octreotide scan shows a tumor in the pancreas or early small bowel.
• Exploratory surgery shows the location of a tumor.
• An endoscopic ultrasound shows a tumor in the pancreas or early small bowel.

Review Date: 05/04/2006
Reviewed By: Jenifer K. Lehrer, MD, Department of Gastroenterology, Frankford-Torresdale Hospital, Jefferson Health System, Philadelphia, PA. Review provided by VeriMed Healthcare Network.