Graves disease

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Endocrine glands

Graves' disease

Thyroid enlargement - scintiscan

Thyroid gland

Diffuse thyrotoxic goiter

• Protruding eyes (less common in children)
• Weight loss
• Increased appetite
• Nervousness
• Restlessness
• Heat intolerance
• Increased sweating
• Fatigue
• Muscle weakness
• Double vision
• Eye irritation
• Breast enlargement in men (possible)
• Tremor
• Frequent bowel movements
• Menstrual irregularities in women
• Goiter (possible)

Physical examination shows an increased heart rate. Examination of the neck may show thyroid enlargement (goiter).

• Serum TSH is decreased
• Serum T3, free T4 are higher than normal
• Radioactive iodine uptake is usually high

• TSI
• Orbit CT scan or ultrasound

Review Date: 08/08/2006
Reviewed By: Robert Hurd, MD, Department of Biology, College of Arts and Sciences, Xavier University, Cincinnati, OH. Review provided by VeriMed Healthcare Network