Hypothyroidism - primary

• A
• B
• C
• D
• E
• F
• G
• H
• I
• J
• K
• L
• M
• N
• O
• P
• Q
• R
• S
• T
• U
• V
• W
• X
• Y
• Z

Primary and secondary hypothyroidism

Thyroid gland

The purpose of treatment is to replace the deficient thyroid hormone. Levothyroxine (T4) is the most commonly used medication, but a preparation of T3 is also available. Most people feel their best when TSH is brought into the 1 to 2 mcIU/mL range. People get the lowest dose that is effective in relieving symptoms and normalizing blood tests.

Life-long therapy is needed. Relapses will occur if therapy is interrupted. Medication must be continued even when symptoms go away.

After replacement therapy has begun, report any symptoms of increased thyroid activity (hyperthyroidism), such as restlessness, rapid weight loss, heat intolerance, and sweating.

Myxedema coma is treated by intravenous thyroid replacement and steroid therapy. Supportive therapy (oxygen, assisted ventilation, and fluid replacement) and intensive care nursing may be indicated.

With early treatment, the condition can be completely controlled. However, relapses will occur if the medication is not continued. Myxedema coma can result in death.

Myxedema coma, the most severe form of hypothyroidism, is rare. It may be caused by an infection, illness, exposure to cold, or certain medications. Symptoms and signs of myxedema coma include:

• Unresponsiveness
• Decreased breathing
• Low blood pressure
• Low blood sugar
• Below-normal temperature

Other complications include:

• Heart disease
• Increased risk of infection
• Infertility
• Miscarriage
• Pituitary tumors

Call your health care provider if signs or symptoms of hypothyroidism or myxedema are present

Call your health care provider if restlessness, rapid weight loss, heat intolerance, rapid heart rate, excessive sweating, or symptoms of hyperthyroidism occur after beginning thyroid replacement.

Review Date: 05/12/2006
Reviewed By: Robert Hurd, MD, Department of Biology, College of Arts and Sciences, Xavier University, Cincinnati, OH. Review provided by VeriMed Healthcare Network.