Retroperitoneal fibrosis


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Male urinary system
Male urinary system
Alternative Names

Idiopathic retroperitoneal fibrosis; Ormond's disease


Symptoms

Early symptoms:

  • Dull pain in the abdomen that increases with time
  • Swelling of one leg
  • Decreased circulation in the legs leading to pain and discoloration
  • Severe abdominal pain with hemorrhage due to ischemic bowel

Later symptoms:

  • Decreased urine output
  • Total lack of urine (anuria)
  • Nausea, vomiting, changes in thinking caused by kidney failure and the resulting build-up of toxic chemicals in the blood.

Signs and tests
  • Serum BUN and creatinine showing elevated levels
  • Kidney ultrasound showing hydronephrosis (distention of the kidney pelvis because of fluid accumulation) and a mass
  • Excretory urography showing compression and deviation of the ureters
  • Abdominal CT scan (the best test to reveal the retroperitoneal mass)
  • MRI (compares well to the CT scan)
  • Biopsy showing either retroperitoneal fibrosis or a cancerous tumor


Review Date: 06/03/2005
Reviewed By: Thomas A. Owens, M.D., Departments of Internal Medicine and Pediatrics, Duke University Medical Center, Durham, NC. Review provided by VeriMed Healthcare Network.


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