Factor XII (Hageman factor) deficiency

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Blood clots

This is an inherited disorder with no symptoms. It does not cause abnormal bleeding in the affected person, but the blood takes longer than normal to clot (coagulate) in a test tube. It results from a deficiency of the plasma protein factor XII.

Factor XII deficiency is a rare hereditary disorder that is usually found when clotting tests are done for routine screening. It is not associated with abnormal bleeding.

Review Date: 04/15/2005
Reviewed By: Rita Nanda, MD, Department of Medicine, Section of Hematology/Oncology, University of Chicago Medical Center, Chicago, IL. Review provided by VeriMed Healthcare Network.