Acquired platelet function defect

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Blood clot formation

Blood clots

Acquired qualitative platelet disorders; Acquired disorders of platelet function

Treatment is directed at the cause of the abnormality. Dialysis reduces the bleeding tendency if the cause is renal failure. Platelet transfusions or plateletpheresis (removal of platelets from the blood and replacement with donated platelets) may be indicated in myeloproliferative disorders. Medication-induced platelet abnormalities require discontinuation of the medication.

Treatment of the cause of the abnormality usually corrects the defect.

• Prolonged bleeding
• Severe anemia

• If bleeding of unknown cause is present.
• If symptoms worsen or do not improve after treatment of an acquired platelet function defect.

Review Date: 04/15/2005
Reviewed By: Rita Nanda, MD, Department of Medicine, Section of Hematology/Oncology, University of Chicago Medical Center, Chicago, IL. Review provided by VeriMed Healthcare Network.