Congenital protein C or S deficiency

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Blood clot formation

Blood clots

Treatment for deep venous thrombosis includes therapy with heparin and warfarin. Warfarin is usually given preventatively after a first clotting episode in patients identified to have this disorder.

The outcome is usually good with treatment, but recurrences can occur.

• Pulmonary embolism
• Recurrent venous clots
• Recurrent pregnancy loss
• Childhood stroke

In rare cases, initial anticoagulation with warfarin can cause transient increased coagulation with severe skin lesions. Patients are at risk if not adequately anticoagulated with heparin prior to taking warfarin.

Call your health care provider if symptoms develop that are suggestive of intravenous clotting (i.e., swelling and redness of the leg).

Review Date: 04/15/2005
Reviewed By: Rita Nanda, MD, Department of Medicine, Section of Hematology/Oncology, University of Chicago Medical Center, Chicago, IL. Review provided by VeriMed Healthcare Network.