Acute cytomegalovirus (CMV) infection

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Antibodies	Infectious mononucleosis	Infectious Mononucleosis #3	Mononucleosis, photomicrograph of cell
Mononucleosis, photomicrograph of cells	Mononucleosis, photomicrograph of cells	Mononucleosis - mouth

CMV Mononucleosis; Cytomegalovirus (CMV)

• Fever
• Sore throat
• Enlarged lymph nodes, especially in the neck
• Malaise (vague ill feeling)
• Frequent tiredness or fatigue
• Loss of appetite
• Muscular aches or stiffness

• Jaundice (yellow cast to skin)
• Headache
• Neck stiffness
• Sensitivity to light
• Cough
• Shortness of breath
• Chest pain
• Rapid heart rate
• Irregular heart rate
• Hives

Your health care provider will perform a physical exam and feel your belly area. The liver and spleen may be tender when they are gently pressed (palpated). There may be a skin rash.

Special lab tests will be done to check for substances in your blood that are produced by CMV. This includes a CMV ELISA antibody test and CMV serum PCR test.

A monospot test should be negative in CMV mononucleosis.

Blood tests show a low number of platelets and a high number of certain white blood cells.

A chemistry panel may show abnormal liver enzymes.

Review Date: 09/18/2006
Reviewed By: Hilary M. Babcock, M.D., Medical Director of Occupational Infection Control, Barnes-Jewish and St. Louis Children's Hospitals; Instructor of Medicine, Infectious Disease Division, Washington University School of Medicine, St. Louis, MO. Review provided by VeriMed Healthcare Network.