Granuloma inguinale

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Skin layers

Donovanosis

A complete cure of granuloma inguinale requires fairly long treatment. Most treatment courses run 3 weeks or until the lesions have completely healed. The antibiotics used include:

• Tetracycline or doxycycline
• Sulfamethoxazole
• Gentamicin
• Streptomycin
• Ciprofloxacin
• Erythromycin

Treating this disease early decreases the chances of tissue destruction or scarring.  Untreated disease can lead to complications.

• Genital destruction and scarring
• Genital depigmentation (loss of skin color)
• Permanent genital swelling from lymphatic scarring

Call for an appointment with your health care provider if you have had sexual exposure to a person who is known to have granuloma inguinale, or if you develop symptoms similar to those listed above.

Review Date: 06/17/2005
Reviewed By: Rocio Hurtado, M.D., Division of Infectious Disease, Massachusetts General Hospital, Boston, MA. Review provided by VeriMed Healthcare Network.