Toxoplasmosis

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Antibodies

Congenital toxoplasmosis

Slit-lamp exam

In non-immunosuppressed people:

• mild illness with fever, resembling mononucleosis
• enlarged lymph nodes in the head and neck
• headache
• sore throat
• muscle pain

In congenital infection:

• central nervous system disorders
• enlarged liver or spleen
• rash, fever, jaundice, anemia
• inflammation of the retina of the eye
• psychomotor and learning disorders (may not appear until later)

In an immunosuppressed person:

• brain lesions are associated with fever, headache, confusion, seizures, and abnormal neurological findings
• retinal inflammation causing blurred vision

Tests to determine infection or presence of cysts:

• serologic titers for toxoplasmosis
• MRI of head
• cranial CT scan
• brain biopsy
• slit lamp examination reveals characteristic retinal lesions

Review Date: 02/13/2006
Reviewed By: Monica Gandhi, M.D., M.P.H., Assistant Professor, Division of Infectious Diseases, UCSF, San Francisco, CA. Review provided by VeriMed Healthcare Network.