Sepsis

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Antibodies

Systemic inflammatory response syndrome (SIRS)

• Fever or hypothermia (low body temperature)
• Hyperventilation
• Chills
• Shaking
• Warm skin
• Skin rash
• Rapid heart beat
• Confusion or delirium
• Decreased urine output

• White blood cell count that is low or high
• Platelet count that is low
• Blood culture that is positive for bacteria
• Blood gases that reveal acidosis
• Kidney function tests that are abnormal (early in the course of disease)

• Peripheral smear may demonstrate a low platelet count and destruction of red blood cells.
• Fibrin degradation products are often elevated, a condition that may be associated with a tendency to bleed.
• Blood differential -- with immature white blood cells seen

Review Date: 08/08/2006
Reviewed By: D. Scott Smith, M.D., MSc, DTM&H, Chief of Infectious Disease & Geographic Medicine, Kaiser Redwood City, CA & Adjunct Assistant Professor, Stanford University. Review provided by VeriMed Healthcare Network.