Duchenne muscular dystrophy

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X-linked recessive genetic defects

X-linked recessive genetic defects - how boys are affected

X-linked recessive genetic defects - how girls are affected

Pseudohypertrophic muscular dystrophy; Muscular dystrophy - Duchenne type

There is no known cure for Duchenne muscular dystrophy. Treatment is aimed at control of symptoms to maximize the quality of life. Gene therapy may become available in the future.

Activity is encouraged. Inactivity (such as bedrest) can worsen the muscle disease. Physical therapy may be helpful to maintain muscle strength and function. Orthopedic appliances (such as braces and wheelchairs) may improve mobility and the ability for self-care.

The stress of illness can often be helped by joining a support group where members share common experiences and problems. See muscular dystrophy - support group. The Muscular Dystrophy Association is an excellent source of information on this disease.

Duchenne muscular dystrophy results in rapidly progressive disability. Death usually occurs by age 25, typically from respiratory (lung) disorders.

• Deformities
• Permanent, progressive disability
  • Decreased mobility
  • Decreased ability for self-care
• Mental impairment (varies, usually minimal)
• Pneumonia or other respiratory infections
• Respiratory failure
• Cardiomyopathy
• Congestive heart failure (rare)
• Heart arrhythmias (rare)

Call your health care provider if your child has symptoms that indicate Duchenne muscular dystrophy.

Call your health care provider if symptoms worsen, or new symptoms develop, particularly fever with cough or breathing difficulties.

Review Date: 08/11/2006
Reviewed By: Brian Kirmse, MD, Mount Sinai School of Medicine, Department of Human Genetics, New York, NY. Review provided by VeriMed Healthcare Network.