Senile cerebral amyloid angiopathy

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Amyloidosis on the fingers

Arteries of the brain

Senile cerebral amyloid angiopathy (CAA) is neurological condition in which amyloid protein is deposited onto the walls of the arteries of the brain. CAA increases the risk of bleeding into the brain (hemorrhagic stroke).

Amyloidosis - cerebral; CAA

Senile cerebral amyloid angiopathy is a cause of lobar intracerebral hemorrhage (bleeding in a localized area of the brain, a form of stroke) in the elderly. There may be multiple episodes of bleeding, which may occur over a period of many months. The symptoms occur because bleeding in the brain harms brain tissue.

The cause is unknown. Amyloid protein is deposited in the arterial walls of the brain, and there are often no deposits elsewhere in the body. The major risk factor is age. The incidence is much greater in people older than 60.

Review Date: 08/07/2006
Reviewed By: Daniel Kantor, M.D., Director of the Comprehensive MS Center, NeuroscienceInstitute, University of Florida Health Science Center, Jacksonville, FL. Review provided by VeriMed Healthcare Network.