Immunodeficiency disorders

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Antibodies

Increasing age also reduces the effectiveness of the immune system to some degree. Immune system tissues (particularly lymphoid tissue such as the thymus) shrink, and there is also reduced lymphocyte number and activity.

The following list contains conditions and diseases that can result in an immunodeficient state:

• Ataxia-telangiectasia
• DiGeorge syndrome
• Chediak-Higashi syndrome
• Job syndrome
• Leukocyte adhesion defects
• Panhypogammaglobulinemia
  • Bruton disease
  • Congenital agammaglobulinemia
• Selective deficiency of IgA
• Combined immunodeficiency disease
• Wiscott-Aldrich syndrome
• Complement deficiencies

Review Date: 06/13/2005
Reviewed By: Thomas A. Owens, M.D., Departments of Internal Medicine and Pediatrics, Duke University Medical Center, Durham, NC. Review provided by VeriMed Healthcare Network.