Erythema nodosum

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Erythema nodosum associated with sarcoidosis

Erythema nodosum on the foot

The characteristic tender, red nodules of erythema nodosum usually appear on the shins:

• One or more nodules
• Painful, reddened
• Located on the anterior surface of the lower leg
• Occasionally located on the arms or trunk
• May feel warm to touch
• Not ulcerated

Accompanying symptoms include the following:

• Fever
• General ill feeling (malaise)
• Joint aches
• Skin redness , inflammation, or irritation
• Swelling of the leg or other affected area

The diagnosis is primarily based on the appearance of the skin nodules. Biopsy of a nodule may show characteristic changes (septal panniculitis).

Review Date: 10/26/2006
Reviewed By: Michael S. Lehrer, M.D., Department of Dermatology, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network.