Macroamylasemia


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Definition

Macroamylasemia is the buildup of a molecule, called macroamylase, in the blood.


Causes, incidence, and risk factors

Macroamylase is a molecule that consists of an enzyme, called amylase, bound to a protein. Because it is relatively large, macroamylase is filtered very slowly from the blood by the kidneys.

Macroamylasemia has been associated with:

  • Celiac disease
  • Ulcerative colitis
  • Rheumatoid arthritis
  • Lymphoma
  • HIV infection
  • Monoclonal gammopathy


Review Date: 10/18/2006
Reviewed By: Jenifer K. Lehrer, MD, Department of Gastroenterology, Frankford-Torresdale Hospital, Jefferson Health System, Philadelphia, PA. Review provided by VeriMed Healthcare Network.


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