Graft-versus-host disease

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Antibodies

GVHD

Acute :

• Skin rash
• Diarrhea
• Abnormal liver function test
• Increased susceptibility to infection

Symptoms usually begin within 2 months after transplantation.

Chronic :

• Skin rash
• Dermatitis
• Hair loss
• Liver damage
• Dry eyes and dry mouth
• Increased susceptibility to infections
• Possibly lung and gastrointestinal disorders

Chronic symptoms start more than 3 months after transplant.

Review Date: 06/03/2005
Reviewed By: Thomas A. Owens, M.D., Departments of Internal Medicine and Pediatrics, Duke University Medical Center, Durham, NC. Review provided by VeriMed Healthcare Network.