Hyperimmunoglobulin E syndrome

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Job syndrome; Hyper IgE syndrome

There is no known cure for the condition. The goal of treatment is to control the recurrent infections. Medications include antibiotic treatment. Antifungal agents and antiviral agents are prescribed when appropriate.

Sometimes, surgical drainage of abscesses is needed.

IV gamma globulin may help to build up the immune system temporarily when there are severe infections.

Job syndrome is a lifelong chronic condition. Each new infection requires treatment.

• Repeated infections
• Infection spreads throughout the body (see sepsis )

Call your health care provider if you are experiencing or observing a collection of the above signs and symptoms.

Review Date: 08/03/2005
Reviewed By: Frederic F. Little, M.D., Department of Allergy and Pulmonary/Critical Care Medicine, Boston University School of Medicine, Boston, MA. Review provided by VeriMed Healthcare Network.