Congenital afibrinogenemia

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• Bruising
• Nosebleeds
• Excessive bleeding following injury or surgery
• Gastrointestinal bleeding
• Bleeding in joints
• Miscarriage

If a bleeding disorder is suspected, laboratory tests are performed to determine the type and extent. This disorder usually shows up in childhood, often at birth.

Tests include:

• PTT
• Prothrombin time (PT)
• Clotting time
• Fibrinogen levels
• Thrombin time
• Reptilase time
• Bleeding time

All of these tests are abnormal in afibrinogenemia.

Review Date: 04/15/2005
Reviewed By: Rita Nanda, MD, Department of Medicine, Section of Hematology/Oncology, University of Chicago Medical Center, Chicago, IL. Review provided by VeriMed Healthcare Network.