Urticaria pigmentosa

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Dermatographism - close-up	Dermatographism on the arm	Dermatographism on the back	Mastocytosis, diffuse cutaneous
Urticaria pigmentosa - close-up	Urticaria pigmentosa in the armpit	Urticaria pigmentosa on the chest

Mastocytosis; Mastocytoma

• Appearance of brownish lesions on skin
• Welt or hive formation when lesions are rubbed or scratched
• Blister formation over lesion when it is rubbed
• Facial flushing

• Diarrhea
• Fast heart rate
• Headache
• Fainting (syncope)

• Urine histamine -- shows elevated levels of histamine
• Skin biopsy -- confirms the presence of increased number of mast cells

Review Date: 10/23/2006
Reviewed By: Kevin Berman, MD, PhD, Associate, Atlanta Center for Dermatologic Disease, Atlanta, GA. Review provided by VeriMed Healthcare Network.