MMR - vaccine

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(Page 2)

Immunizations

Measles on the back

Rubella on an infant's back

• fever (1 in 6 children)
• rash (1 in 20)
• swollen glands (rare)
• seizure (1 in 3,000)
• joint pain/stiffness (1 in 4, usually young women)
• low platelet count/bleeding (1 in 30,000)

Severe adverse effects may include:

• allergic reaction (less than 1 per million)
• long-term seizure/brain damage/deafness (so rare that the association with the vaccine is questionable)

Despite considerable publicity, there is no evidence linking MMR vaccination with the development of autism. The Centers for Disease Control & Prevention (CDC) website provides extensive information on this matter.

The potential benefits from receiving the MMR vaccine far outweigh the potential adverse effects. Measles, mumps, and rubella are all very serious illnesses and each may have complications resulting in lifetime disabilities or even death.

The incidence of such complications, related to having the actual diseases, is far greater than the potential of developing serious, or even moderate, adverse effects due to the MMR vaccine.

WHEN TO DELAY OR NOT GIVE THE VACCINE

If the child is ill, with something more serious than just a cold, immunization may be delayed. Health care providers need to be informed of any problems that may have occurred with the first MMR injection prior to receiving the second MMR.

MMR should not be given to individuals with:

• an allergy to gelatin or the antibiotic neomycin serious enough to require medical treatment
• an immune deficiency caused by cancer, leukemia, lymphoma, or HIV
• an immune deficiency caused by taking prednisone, other steroids, chemotherapy, radiation therapy, or other immunosuppressant drugs
• a woman who is, or possibly may become, pregnant within the next 28 days

People who have received transfusions or other blood products (including gamma globulin) or who have had low platelet counts should discuss the proper timing of MMR vaccine with their physician.

SYMPTOMS AFTER THE SHOT

Watch for and be familiar with how to care for a fever, joint pain/stiffness, minor gland enlargement/tenderness, or minor redness/soreness at the injection site. If a rash develops without other symptoms, no treatment is necessary, and it should resolve within several days.

CALL YOUR DOCTOR IF:

• You are uncertain if the MMR should be given, withheld, or delayed for a specific individual
• You have moderate or serious symptoms after an MMR injection
• Other symptoms, not commonly associated with potential adverse effects of the MMR, develop
• You have any questions or concerns related to MMR immunizations

Review Date: 06/16/2005
Reviewed By: John Goldenring, M.D., M.P.H., Department of Pediatrics, Children's Hospital, San Diego, CA. Review provided by VeriMed Healthcare Network.