Sex-linked recessive

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Genetics

For a given birth, if the mother is a carrier and the father has the disease:

• 25% chance of a healthy boy
• 25% chance of a boy with the disease
• 25% chance of a carrier female
• 25% chance of a girl with the disease

If the mother has the disease and the father has the disease:

• 100% chance of the child having the disease, whether boy or girl.

The odds of either of these two scenarios are so low that x-linked recessive diseases are sometimes referred to as “male only” diseases, although this is not technically correct.

Review Date: 05/31/2006
Reviewed By: Brian Kirmse, MD, Mount Sinai School of Medicine, Department of Human Genetics, New York, NY. Review provided by VeriMed Healthcare Network.