Simian crease


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Simian crease
Simian crease
Alternative Names

Single palmar crease


Home Care


Call your health care provider if


What to expect at your health care provider's office

An infant with a simian crease may have other symptoms and signs that, when taken together, define a specific syndrome or condition. Diagnosis of that condition is based on a family history, medical history, and thorough physical evaluation.

Your doctor may ask questions such as:

  • Is there a family history of Down syndrome or other disorder associated with a simian crease?
  • Have other family members had a simian crease and no other abnormality?
  • What was the pregnancy like?
  • Did the mother use alcohol while pregnant?
  • What other symptoms or physical abnormalities are present?

Based on the answers to these questions, the medical history, and the results of the physical exam, further testing may be necessary.



Review Date: 05/10/2006
Reviewed By: Daniel Rauch, MD, FAAP, Director, Pediatric Hospitalist Program, Associate Professor of Pediatrics, NYU School of Medicine, New York, NY. Review provided by VeriMed Healthcare Network.


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