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Mononucleosis spot test

From DrKoop's partner site on cholesterol, CholesterolNetwork.com
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Mononucleosis, photomicrograph of cells
Mononucleosis, photomicrograph of cells
Mononucleosis - view of the throat
Mononucleosis - view of the throat
Alternative Names

Monospot test; Heterophile antibody test


Normal Values

Normal results are negative, which is indicated by a titer ratio of less than 1:40.


What abnormal results mean

A positive test (titer greater than 1:40) usually indicates infectious mononucleosis. On rare occasions, false-positive tests may be seen with the following:

  • Leukemia or lymphoma
  • Rubella
  • Hepatitis
  • Systemic lupus erythematosus (SLE)

Review Date: 06/09/2005
Reviewed By: Kenneth Wener, M.D., Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, MA. Review provided by VeriMed Healthcare Network.

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