LDH

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Lactate dehydrogenase; Lactic acid dehydrogenase

Normal values may vary slightly from laboratory to laboratory. A typical range is 105-333 IU/L (international units per liter).

Higher-than-normal levels may indicate:

• cerebrovascular accident (CVA, stroke)
• heart attack
• hemolytic anemia
• hypotension
• infectious mononucleosis
• intestinal ischemia (blood deficiency) and infarction (tissue death)
• liver disease (for example, hepatitis )
• muscle injury
• muscular dystrophy
• neoplastic (new abnormal tissue formation) states
• pancreatitis
• pulmonary infarction (tissue death)

If the LDH level is elevated, the health care provider will often recommend measurement of LDH isoenzymes.

Additional conditions under which the test may be performed:

• anemia of vitamin B-12 deficiency
• megaloblastic anemia
• pernicious anemia

Review Date: 04/15/2005
Reviewed By: Rita Nanda, MD, Department of Medicine, Section of Hematology/Oncology, University of Chicago Medical Center, Chicago, IL. Review provided by VeriMed Healthcare Network.