ACE levels

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Blood test

Serum angiotensin-converting enzyme; SACE

Normal values vary with age and with the test method used. Typically, adults have ACE levels less than 40 micrograms/L.

This test is often used to help diagnose sarcoidosis, a condition in which ACE levels are increased 75% of the time. Elevated ACE levels may also be seen in several other disorders, including:

• Active histoplasmosis
• Alcoholic cirrhosis
• Amyloidosis
• Asbestosis
• Berylliosis
• Diabetes
• Gaucher's disease
• Hodgkin's disease
• Hyperthyroidism
• Idiopathic pulmonary fibrosis
• Leprosy
• Myeloma
• Primary biliary cirrhosis
• Pulmonary embolism
• Scleroderma
• Silicosis
• Tuberculosis

• Steroid therapy (usually prednisone)
• Response to therapy for sarcoidosis

Review Date: 03/02/2006
Reviewed By: David A. Kaufman, M.D., Assistant Professor, Division of Pulmonary, Critical Care & Sleep Medicine, Mount Sinai School of Medicine, New York, NY. Review provided by VeriMed Healthcare Network.