CSF VDRL test

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CSF test for syphilis

Venereal Disease Research Laboratory slide test - CSF

Sometimes, people with syphilis can have normal CSF-VDRL test result. This is called a "false-negative" result. Therefore, a negative test does not always rule out neurosyphilis. Other markers of inflammation, such as elevated protein levels or excess white blood cells, may be used to diagnose neurosyphilis.

A reactive VDRL test when using a CSF sample indicates neurosyphilis.

Review Date: 06/10/2005
Reviewed By: Eleftherios Mylonakis, M.D., Division of Infectious Disease, Massachusetts General Hospital, Boston, MA. Review provided by VeriMed Healthcare Network.