Synovial fluid analysis

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Joint aspiration

Synovial fluid analysis is a battery of tests performed on synovial (joint) fluid to help diagnose and treat joint-related abnormalities.

Joint fluid analysis; Joint fluid aspiration

To obtain the fluid for analysis, a sterile needle is inserted into the joint space through skin that has been specially cleaned. Once in the joint, fluid is aspirated through the needle into a sterile syringe.

Synovial fluid is normally a viscous (thick), straw colored substance found in small amounts in joints, bursae, and tendon sheaths. In the laboratory, the fluid is initially analyzed for color and clarity. It is then examined microscopically for cells (red and white cells), crystals (in the case of gout), and bacteria. In addition, there may be a chemical analysis, and if infection is a concern, a sample will be cultured to see if any bacteria grow.

Abnormal joint fluid may look cloudy or abnormally thick.

Normally, no special preparation is necessary, but contact your health care provider before the test to make sure.

Most health care providers will start by injecting local anesthesia with a small needle, which will sting. The aspiration is done with a larger needle and may also cause some pain. The procedure usually lasts less than one minute.

The test is performed to diagnose the cause of pain or swelling in joints, and to relieve pain from fluid accumulation (usually blood or pus) in the joint.

Common diseases diagnosed with fluid aspiration include infection, gout, and other inflammatory joint conditions. Blood in the joint may be an indication of trauma inside the joint or a systemic bleeding problem. An excess amount of normal synovial fluid can also be a sign of osteoarthritis.

Review Date: 06/07/2005
Reviewed By: Andrew L. Chen, M.D., M.S., Steadman-Hawkins Sports Medicine Foundation, Vail, Co. Review provided by VeriMed Healthcare Network.