Fibrin degradation products

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FDPs; FSPs; Fibrin split products; Fibrin breakdown products

The result is normally less than 10 mcg/mL.

Note: mcg/mL = micrograms per milliliter

Increased FDPs may indicate primary or secondary fibrinolysis (clot-dissolving activity) from such conditions as:

• Abruptio placentae
• Burns
• Congenital heart disease
• Disseminated intravascular coagulation (DIC)
• Following cardiopulmonary (heart and lungs) pump surgery
• Following massive blood transfusion
• Hypoxia
• Infections
• Intrauterine fetal death
• Leukemia
• Liver disease (see cirrhosis )
• Portacaval shunt
• Preeclampsia
• Renal disease (see kidney failure )
• Septicemia
• Thromboembolic states
• Transplant rejection
• Transfusion reaction

Review Date: 03/09/2007
Reviewed By: Mark Levin, MD, Hematologist and Oncologist, Newark, NJ. Review provided by VeriMed Healthcare Network.