Metyrapone test

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Blood:

• 11-deoxycortisol increased to more than 3 mcg/dL
• Cortisol less than 7 mcg/dL
• ACTH greater than 75 pg/mL

• Baseline excretion of urinary 17-OHCS more than doubled

Normal value ranges may vary slightly among different laboratories.

The test may be useful in distinguishing between the different types of Cushing's syndrome. In addition, it can sometimes help diagnose adrenal insufficiency.

Review Date: 03/03/2006
Reviewed By: David Juan, MD, Specializing in Endocrinology Issues, Good Hand Medical Center and Alperin Medical Clinics, Santa Clara, CA. Review provided by VeriMed Healthcare Network.