Renin

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Kidney - blood and urine flow

Plasma renin activity; Random plasma renin; PRA

Normal values range from 1.9 to 3.7 ng/ml/hour. Normal value ranges may vary slightly among different laboratories.

Note: ng/ml/hour = nanograms per milliliter per hour

Higher-than-normal levels may indicate:

• Addison's disease
• Cirrhosis
• Essential hypertension
• Hemorrhage (bleeding)
• Hypokalemia
• Malignant hypertension
• Renin-producing renal tumors
• Renovascular hypertension

Lower-than-normal levels may indicate:

• Salt-retaining steroid therapy
• ADH therapy
• Salt-sensitive essential hypertension

Additional conditions under which the test may be performed include primary hyperaldosteronism.

Review Date: 02/03/2006
Reviewed By: Charles Silberberg, DO, Private Practice specializing in Nephrology, Affiliated with New York Medical College, Division of Nephrology, Valhalla, NY. Review provided by VeriMed Healthcare Network.