Thrombolytic therapy

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Stroke

Thrombus

The decision to give the drug is based upon your medical history, a physical exam that shows a significant stroke, and a brain CT scan to make sure there is no bleeding.

tPA is not given if someone is having a hemorrhagic stroke because this could worsen the stroke by causing increased bleeding.

RISKS

There are various drugs used for thrombolytic therapy, but tPA is used most often. Others drugs include Streptokinase (SK), Reteplase, Tenecteplase, Urokinase, Lanoteplase, and Staphylokinase.

Hemorrhage or bleeding is the most common risk. Minor bleeding from the gums or nose can occur in approximately 25% of people who receive the drug. Bleeding into the brain occurs approximately 1% of the time. This risk is the same for both stroke and heart attack patients.

CONTACT A HEALTH CARE PROVIDER OR CALL 911

Heart attacks and strokes are medical emergencies. The sooner treatment with tPA takes place, the better the chance for a good outcome.

See also:

• Stroke
• Heart attack

Review Date: 07/17/2006
Reviewed By: Glenn Gandelman, MD, MPH, Assistant Clinical Professor of Medicine, New York Medical College, Valhalla, NY. Review provided by VeriMed Healthcare Network.