Nicotine withdrawal


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Alternative Names

Withdrawal from nicotine


Treatment

There are several strategies for treating nicotine withdrawal. Nicotine supplementation in the form of gum or patch can be helpful. A variety of other agents have also been used with some success in maintaining abstinence and reducing withdrawal symptoms.

These agents include clonidine, antidepressants such as fluoxetine (Prozac), and buspirone (Buspar). Bupropion (Zyban) was approved in 1996 by the Food and Drug Administration as a treatment for nicotine dependence.

Using bupropion or nicotine replacement therapies alone doubles the odds of successful quitting. Using a combination of these methods increases success rates even more.



Very recently, the FDA approved a new medication for smoking cessation, Chantix. It acts to block the effects of nicotine and eases withdrawal symptoms. There is some evidence that it may be more helpful in quitting smoking than buspirone.

Buproprion and other antidepressants are not habit-forming, and may help reduce the possibility that nicotine withdrawal may lead to depression.

Since nicotine itself has antidepressant effects - and many smokers unknowingly smoke to self-medicate depression - use of antidepressants to relieve withdrawal may be particularly helpful.

A screening for depression may also be helpful to ensure proper treatment and increase the odds of maintaining abstinence.

People trying to quit smoking often become discouraged when they don't succeed at first. Research shows that the more times you try, the more likely you are to succeed - so don't give up!


Support Groups


Expectations (prognosis)

Nicotine withdrawal is short-lived and should pass in time. While withdrawal is the most uncomfortable part of quitting, the real challenge is beating long-term cravings and staying abstinent.


Complications

The most likely complication will be a return to smoking. Weight gain due to increased eating also may occur. This is much less unhealthy than continuing to smoke, and those with concerns about weight should address them while quitting so that they do not undermine their attempts to stay away from cigarettes.


Calling your health care provider

See your health care provider if you wish to stop smoking, or have already done so and are experiencing withdrawal symptoms. Your provider can help provide treatments, some of which are only available by prescription.



Review Date: 05/17/2006
Reviewed By: Paul Ballas, D.O., Department of Psychiatry, Thomas Jefferson University Hospital, Philadelphia, PA. Review provided by VeriMed Healthcare Network.

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