Lung Capacity Declines Faster With Diabetes

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"On the other hand, we found diabetes severity, as indicated by intensity of anti-diabetic treatment, was associated with greater rate of FVC decline. Patients on insulin treatment, alone or with oral medications, had the greatest decline in forced vital capacity compared to their non-diabetic counterparts," Yeh explained.

In an accompanying editorial, Dr. Connie Hsia, of the University of Texas Southwestern Medical Center, cautioned that using inhaled insulin might trigger or exacerbate the pulmonary dysfunction found in people with diabetes.

"However, since none of our study participants were on inhaled insulin, our study did not have direct implications on the use or absorption of inhaled insulin," Yeh said.

Umpierrez pointed out that the use of inhaled insulin needs more study. "The future of inhaled insulin for treatment of diabetes is uncertain; however, some pharmaceutical companies continue to investigate the safety and efficacy of inhaled insulin as an alternative of insulin injections," he noted.

Diminished lung capacity may lead to lower oxygen delivery to all body tissues, he noted, although the drop in lung function among diabetics in this study appears to be small. However, in elderly patients with long-standing diabetes, impairment of lung capacity could worsen the risks of adverse outcomes should the elderly diabetic develop pneumonia, heart failure, volume overload or vascular complications, he added.

"Traditionally, the lung is not treated as a target organ for diabetes complication. Based on the current study, we suggest physicians add lung function on the watch list as they care for their diabetes patients," Yeh said.

More information

For more on diabetes, visit the American Diabetes Association.