Genetic Disorder May Hold Key to Heat Stroke Cure

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"We found that destructive cycles of calcium leakage and excess free radical production damage mitochondria and contribute to the deterioration of muscle function in aged animals," Dirksen said. "In successfully constructing the first mouse model of human MH, we unwittingly generated the first animal model of heat stroke that will undoubtedly be tremendously useful in better understanding these disorders and in accelerating the design of safe and effective treatments for both conditions."

More information

The U.S. Centers for Disease Control and Prevention has more about protecting yourself from extreme heat.